Retroviridae

Saturday, January 31, 2009

Genome Structure and Virion Properties

Genome Structure
The genome of retroviridae is dimeric, unsegmented and contains a single molecule of linear. The genome is a positive-sense, single-stranded RNA. Minor species of non-genomic nucleic acid are also found in virions.


Virion Properties
Virions consist of an envelope, a nucleocapsid, and a nucleoid. Virus capsid is enveloped. Virions are spherical to pleomorphic. They are measured 80-100 nm in diameter. Surface projections are densely dispersed, small or distinctive glycoprotein spikes that cover evenly the surface. Surface projections are 8 nm long. The nucleoid is concentric, or eccentric. The core is spherical. The single-stranded, linear RNA is found to be 7-12 kb in size.


Picture extracted: http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/Retroviruses.html

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